The drug "Bicillin-5" refers to penicillinantibiotics. The medicine shows activity against gram-negative microorganisms that cause gonorrhea, meningitis, as well as Gram-positive streptococci, staphylococci, diphtheria and other microbes and anaerobic spore-forming ones. The drug is powerless against microorganisms producing penicillinase.

The majority of gram-negative microbacteria, viruses, fungi and other protozoa are resistant to the action of the drug.

Preparation "Bicillin 5": instructions and pharmacokinetics

Antibiotic is available in the form of a solution forinjections. With intramuscular injection, a drug depot is created in the muscle tissue. The high-dose agent is concentrated in the body immediately after the injection, and the therapeutic concentration of the drug remains in the blood of the vast majority of patients (adults and children) for 28 days.

The medicine is excreted from the body mainly with the help of kidneys. A small amount of the drug comes with sweat, phlegm, saliva. The medication can penetrate into breast milk.

Preparation "Bicillin 5": instructions and indications

The drug is prescribed for therapyInfectious diseases caused by antibiotic-sensitive microorganisms. The use of the drug is indicated for year-round prophylaxis of rheumatism in children and adults.

Preparation "Bicillin 5": instructions for use

Before prescribing the drug, the patient is tolerated. Antibiotic is intended only for intramuscular injection.

As for the dosages of the medicine "Bicillin"the instruction for use recommends that children from 3 to 8 years of age be administered 600,000 units of the drug once every three weeks. Older children double the dose and apply once a month. Adults inject one and a half thousand units of medication every 4 weeks.

Drug injection is more commonit is contraindicated. The usual duration of therapy (depending on the ailment) can last from three months to a year. The drug is injected into the upper part of the buttock, if necessary, two injections are done in different places.

The drug "Bicillin-5": instructions and contraindications

The drug is not prescribed for increasedsensitivity to penicillins, carbapenems, cephalosporins, procaine. The use of an antibiotic is prohibited in hay fever, hives and other allergic manifestations.

The list of side effects of the drug "Bicillin 5"The instructions for use include skin rashes, exfoliative dermatitis, pruritus, fever, angioedema, and other hypersensitivity reactions. In addition to these manifestations, there may be the formation of bronchospasm, the occurrence of dizziness, tinnitus, nausea, headache, diarrhea, glossitis, liver function disorders.

The negative consequences of treatment areinterstitial nephritis, tachycardia, pressure fluctuations, disturbances in myocardial contractility. On the part of the lymphatic system and blood organs, abnormalities such as hemolytic anemia, agranulocytosis, thrombocytopenia, and leukopenia occur.

To local negative phenomena include pain when administered and at the place of use of the drug.

In addition to the above-mentioned side effects,weakened patients, in elderly people with long-term therapy there is a superinfection that is caused by antibiotic-resistant microflora (gram-negative microorganisms, yeast-like fungi).

The effect of the drug on pregnant women and during breastfeeding has not been studied.

When the drug is administered in high doses, hemolytic anemia, neutropenia and increased clotting time may occur in patients with a diagnosis of renal insufficiency.